Candidosis intertriginous B37.2

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 28.05.2024

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Synonym(s)

Candidaintertrigo; Candida intertrigo; Candidosis in the diaper area; intertrigo candidamycetica; Nappy Lingerie; Thrush windelder dermatitis

Definition
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Erosive, macerative infection of the intertrigins (axillae, groin bends, overlapping skin folds; perianal region; submammary) by Candida albicans. Most frequent complication of an intertrigo.

Etiopathogenesis
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In incontinence, diapers lead to maceratively erosive intertrigo at the contact points. Intertriginous candidiasis (candidiasis) is thus a primary irritative disease of multifactorial origin with secondary superinfection by bacteria and yeasts of the genus Candida.

Localization
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V.a. Intertrigines (= Intertrigo candidamycetica), especially submammary, inguinal, axillary, umbilical area, perianal.

Clinical features
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Sharply defined, peripherally scaly erythema. Frequently pustule fringe, spatter-like papulovesicular to pustular satellites in the area.

Diagnosis
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Native preparation (spores, pseudomycel), mycological culture (differentiation on rice agar, chlamydospores). Stool examination for Candida. Serology: Candida haemagglutination test.

Differential diagnosis
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  • Intertrigo: no evidence of yeasts
  • Erythrasma: dry, non-macerative dermatitis; brownish-reddish hue.
  • Pemphigus chronicus benignus familiaris: chronic, macerative, completely therapy-resistant dermatitis, evidence of the concertina phenomenon.
  • Psoriasis intertriginosa: chronic, often macerative, completely therapy-resistant dermatitis. Mostly affecting the perional region; sharp demarcation.
  • Allergic contact dermatitis: acute pruritic dermatitis; possibly weeping; typically satellite lesions.
  • Toxic contact dermatitis: acute pruritic dermatitis; usually cause identifiable; possibly weeping; no satellite lesions.

General therapy
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Informing the patient about favourable factors. In adults, weight reduction!

In infants, use of breathable absorbent diapers. Diaper-free episodes.

Careful personal hygiene.

Mild cleansing measures (vegetable or paraffin-containing oils), dry the nappy area well or blow-dry.

External therapy
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Patients with intertriginous candidiasis are primarily treated topically with imidazole antimycotics such as bifonazole and clotrimazole as well as terbinafine and nystatin. The duration of application varies depending on the preparation, but should always be adhered to. If the treatment period is too short, there is an increased risk of recurrence.

Note(s)
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Candida dubliniensis also forms chlamydial spores on the rice agar. With the detection of chlamydospores, however, the diagnosis of Candida albicans is highly probable, as Candida dubliniensis is rarely found.

Literature
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  1. Halvaee S et al (2018) Investigation of Intertriginous Mycotic and Pseudomycotic (Erythrasma) Infections and Their Causative Agents with Emphasize on Clinical Presentations. Iran J Public Health 47:1406-1412.
  2. Krajewska-Kulak E et al (2003) Difficulties in diagnosing and treating tinea in adults at the Department of Dermatology in Bialystok (Poland).Dermatol Nurs 15:527-530,
  3. Seebacher C et al (2006) Candidosis of the skin. J Dtsch Dermatol Ges 4: 591-596

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 28.05.2024